Multifactorial control of gonadotropin release for induction of oocyte maturation: Influence of gonadotropin-releasing hormone, gonadotropin release-inhibiting factor and dopamine receptors in the catfish, Heteropneustes fossilis

Several external and internal factors contribute to the reproductive success of teleosts, which makes process complex unique. In Indian freshwater catfish, Heteropneustes fossilis, monsoon plays a crucial role as it fine tunes neuroendocrine axis, culminating in oocyte maturation. Therefore, induction maturation requires coordinated interaction among hypothalamic, hypophyseal, peripheral hormones. present investigation, dual control has been demonstrated H. fossilis. The maturational response gravid catfish is inhibited presence dopamine but GnRH evokes ovulation. upregulates expression lhb gene well increases plasma levels LH significantly within 30 minutes its administration. Destruction preoptic region by electrolytic or chemical lesions also causes But this if injected into nucleus preopticus periventricularis-lesioned fishes. These observations support an inhibitory factor, therefore specific receptors have characterized their brain quantified. Dopamine are upregulated dopamine-treated fishes downregulated antagonist (pimozide) injected. study suggests mechanism for secretion catfish. Abolition inhibition necessary release surge, turn stimulates resumption meiosis Thus peptidergic aminergic systems regulate Neuroendocrine regulation ovulation major implications inducing spawning aquaculture.